Calmodulin Activation Limits the Rate of KCNQ2 K+ Channel Exit from the Endoplasmic Reticulum
نویسندگان
چکیده
منابع مشابه
Interaction of calmodulin with Sec61a limits Ca leakage from the endoplasmic reticulum
Frank Erdmann, Nico Schäuble, Sven Lang, Martin Jung, Alf Honigmann, Mazen Ahmad, Johanna Dudek, Julia Benedix, Anke Harsman, Annika Kopp, Volkhard Helms, Adolfo Cavalié*, Richard Wagner* and Richard Zimmermann* Biophysics, Osnabrück University, Osnabrück, Germany, Medical Biochemistry and Molecular Biology, Saarland University, Homburg, Germany, Computational Biology, Saarland University, Saar...
متن کاملCytoplasmic acidification reduces potassium channel activities in the endoplasmic reticulum of rat hepatocytes
Introduction: Intracellular pH (pHi) regulates essentially all aspects of cellular activities. However, it is unknown how endoplasmic reticulum (ER) potassium channels sense pHi. In this study, we investigate the direct effects of pHi on ER potassium channels. Methods: We used channel incorporation into the bilayer lipid membrane method. L-α-phosphatidylcholine, a membrane lipid, was extrac...
متن کاملProtein Sorting upon Exit from the Endoplasmic Reticulum
It is currently thought that all secretory proteins travel together to the Golgi apparatus where they are sorted to different destinations. However, the specific requirements for transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in yeast could be explained if protein sorting occurs earlier in the pathway. Using an in vitro assay that reconstitutes a single...
متن کاملKDEL Receptors Assist Dengue Virus Exit from the Endoplasmic Reticulum.
Membrane receptors at the surface of target cells are key host factors for virion entry; however, it is unknown whether trafficking and secretion of progeny virus requires host intracellular receptors. In this study, we demonstrate that dengue virus (DENV) interacts with KDEL receptors (KDELR), which cycle between the ER and Golgi apparatus, for vesicular transport from ER to Golgi. Depletion o...
متن کاملthe effect of traffic density on the accident externality from driving the case study of tehran
در این پژوهش به بررسی اثر افزایش ترافیک بر روی تعداد تصادفات پرداخته شده است. به این منظور 30 تقاطع در شهر تهران بطور تصادفی انتخاب گردید و تعداد تصادفات ماهیانه در این تقاطعات در طول سالهای 89-90 از سازمان کنترل ترافیک شهر تهران استخراج گردید و با استفاده از مدل داده های تابلویی و نرم افزار eviews مدل خطی و درجه دوم تخمین زده شد و در نهایت این نتیجه حاصل شد که تقاطعات پر ترافیک تر تعداد تصادفا...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.m109.019539